The FDA, along with several studies, warns against the use of Zofran (ondansetron) during pregnancy. Zofran is approved by the FDA to treat nausea and vomiting in cancer patients who are undergoing chemotherapy treatment. This medication is not approved to treat morning sickness in pregnant women but many obstetrician and gynecologists are prescribing the anti-nausea medication “off-label”. At this time there is no state or federal law that prevents doctors from prescribing medications off-label. Zofran is most commonly prescribed to mothers who are suffering from persistent and severe vomiting known as hyperemesis gravidarum--the same disorder Kate Middleton suffered from during both of her pregnancies. Several Studies have indicated that there is a correlation between the use of Zofran early on in the first trimester and congenital heart defects, cleft palates, and craniosynostosis. Craniosynostosis is the premature fusion of two or more bones in the skull. If left untreated this condition may cause eyesight problems and learning disabilities. The Article Anti-Nausea Drug's Use During Pregnancy Could Cause Birth Defects, states the number of unapproved use of Zofran prescriptions during pregnancy is estimated at around 1 million every year. According to a study conducted by researchers at Harvard University, the U.S. Centers for Disease Control, and the Slone Epidemiology Center, women who took Zofran early on during their pregnancy were more than twice as likely to give birth to a child with a cleft palate. In a separate study Danish researchers found that babies who had been exposed to ondansetron were “more than twice as likely to be born with atrial and ventricular septal defects and more than four times as likely to have atrioventricular septal defects.” The article goes on to mention another study conducted as recent as 2014 that appeared in the “Reproductive Toxicology” journal. This study supports the theory of increased risk of birth defects as noted in the abovementioned studies. GlaxoSmithKline, the manufacturer of Zofran, paid $3 million dollars to settle allegations that they unlawfully promoted the anti-nausea drug as a treatment for morning sickness in pregnant women. Glaxo strongly denied promoting the drug in this manner, despite allegations that they had prepared marketing flyers to be distributed to obstetrician and gynecologists offices. As much as we would like to solely rely on the advice of our doctors, the responsibility lies within ourselves to research any medication we take during pregnancy. Just because medication is not labeled with birth defect warnings does not necessarily mean there is no risk. Aeroflow Breastpumps values the health and well-being of your baby. Talk to one of our breast pump specialists today and learn how you can qualify through insurance for a free breast pump to provide the best nourishment for your little one even when you are apart.